Vienna 25. June 2009. onepharm, a Vienna-based biotech company specializing in the development of drugs for the treatment of chronic inflammatory diseases, recently received approval from the BfArM, the German health authority, for the execution of a double-blind, placebo-controlled clinical phase 2 study in periodontal disease.
“We are all very excited about this recent success,” commented Bernhard Küenburg, onepharm´s CEO. “The approval of our phase 2 study by the German BfArM allows us to verify our concept of treating periodontitis with a new approach, targeting the local inflammation”.
Periodontitis – a new treatment regimen with an anti-inflammatory drug
Periodontitis, a destructive inflammation of the periodontal bone, is traditionally treated using mechanical procedures, namely scaling and root planing to remove bacterial plaque. This method is often supported by antibiotic treatment or by the use of disinfectants. While it is widely acknowledged that bacterial infection is one of the main causes for periodontitis, the chronic inflammatory component of the disease has recently also received increasing attention. onepharm’s new therapeutic approach is based on the anti-inflammatory properties of its lead candidate, which has proven to substantially inhibit periodontal bone loss in a ligature induced animal model.
“In this first proof of concept study we will follow clinical and inflammatory parameters over a treatment period of 6 weeks”, explains Angelika Bodenteich, onepharm’s Chief Medical Officer. With this study onepharm intends to strengthen its position in the development of effective drugs in chronic inflammatory diseases.
About onepharm
onepharm was founded jointly by its management and Green Hills Biotechnology in 2005. The company focuses on the development of its lead candidate in periodontitis as well as other chronic inflammatory indications. To this date, onepharm has been able to raise funds exceeding EUR 9.0 million, including equity capital, subsidized loans, and research grants.
Contact
onepharm Research & Development GmbH
Dr. Bernhard Küenburg, CEO
Veterinärplatz 1, Building IA
1210 Wien
Tel.: +43-25077-5900
Fax: +43-25077-5999
bernhard.kueenburg(at)onepharm.com
www.onepharm.com
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